Does statin drugs decrease carotid artery blockage?
It is known statin drugs moderate LDL. My question is, do they run down the amount of plague already formed on the carotid artery? What reduces the plague? Is the carotid artery blockage a slow process? How express does it progress? I’d appreciate it you could share some of the related articles.
No statin drugs do not reduce the amount of plaque surrounded by your carotid vessels. They merely prevent you from making bigger globs of plaque.
Carotid artery plaque formation is different in different nation. If they say you are 80% blocked, I envisage your doctor will follow up often to breed sure you are not making a lot more plaque.
I am a RN, but this is not my specialty.
I am so pleased I come across your question as I will be interested to hear the answers too. Statin drugs affect an enzyme that make cholesterol in the liver. No, it doesn't affect the plaque that have already built up in the arteries. As long as you state a healthy lifestyle, exercise and munch through right by avoiding fatty cholesterol laden foods, and be sure to keep up healthy blood sugar level, the rate at which the plaque builds up will be very gradual. In most cases blockages are found when problems arise and an angioplasty next to stent placement is required. Read these
http://www.webmd.com/hw/stroke/hw224563.asp The carotid obstruction is as a rule due to atherosclerotic lesions. This is related near diabetes, hypertension, hypercholesterolemia , tobacco use, age and familiar factor.
Several pharmacologic therapies are central in its treatment. Aspirin is the cornerstone of antiplatelet treatment for these patients, and there is a growing body of evidence for long-term treatment beside thienopyridine inhibitors.
Additionally , statin therapy should be standard contained by all patients next to evidence of atherosclerotic disease, including those with carotid artery atherosclerosis. There is also adjectives that statin therapy have a positive effect on carotid atherosclerotic lesions. Statin analysis was found to be associate near significant reductions contained by vessel wall thickness and vessel wall nouns.
The largest study to evaluate the effect of statins on carotid stenosis –CAIUS- suggest that the benefit of statin therapy contained by patients with carotid artery atherosclerosis disease may surrounded by part be mediate by morphologic effects on early stages of plaque nouns.
From an invasive standpoint, the percutaneous treatment of carotid atherosclerotic disease has made significant advance since its advent in 1980. It have proven to be safe and preferred approach to patients at elevated surgical risk and may prove to have much wider application.
Carotid impasse may be asymptomatic till the 60% of the artery is blocked. Then the risk of TIA – transient ischemic attack – increases and it is necessary to consider invasive psychiatric help.
As mentioned, the treatment through catheter and stent – percutaneous treatment – of carotid atherosclerotic disease is proven to be safe and still developing trial applications. Medical therapy is essential indeed to reduce the incidence of complications surrounded by severe obstructions and prevent further finance of the disease on early stages.
In summary, statin reduce the plaque size according to the mentioned scientific information contained by early stages .
The carotid artery blockage starts slowly forming the plaque, but can increase the size soon if there is complication inwardly the plaque or some condition that adds up a clug to it. It can also be a tremendously slow process that gives time to create a colateral -alternative- circulation that prevents absence of blood supply due to the carotid obstruction.
You can seize more specifical information in the reference that I attach underneath.
I hope this information would be useful for you,
Fro, MD it have been shown that High doses of Crestor can fall plaque build up , but it takes a long time , I would stick beside aspprin and Plavix